Medical research

RNAi therapy mitigates preeclampsia symptoms

A collaboration of scientists from the University of Massachusetts Medical School, Beth Israel Deaconess Medical Center and Western Sydney University, have shown that an innovative new type of therapy using small interfering ...

Obstetrics & gynaecology

Scientists discover critical molecular biomarkers of preeclampsia

Preeclampsia, a sudden pregnancy complication that can interfere with the blood flow to the placenta and possibly to the fetus, can lead to low birth weight, prematurity and even death. It is also a leading cause of maternal ...

Obstetrics & gynaecology

Lack of a hormone in pregnant mice linked to preeclampsia

(Medical Xpress)—A team of researchers from Singapore, the Netherlands and Turkey has isolated a hormone in pregnant mice that appears to be associated with preeclampsia—a pregnancy-related condition characterized by ...

Medical research

Preeclampsia may share cause with disorders such as Alzheimer's

New research has identified a potential cause of and a better diagnostic method for preeclampsia, one of the most deadly and poorly understood pregnancy-related conditions in the world. The international team, led by researchers ...

Cardiology

A mineral, a metal and a deadly pregnancy condition

Pregnant women with lower concentrations of the trace mineral manganese or higher amounts of the metal cadmium in their blood may be more likely to develop preeclampsia, according to a new study.

Cardiology

Clinical trials beginning for possible preeclampsia treatment

For over 20 years, a team of researchers at Lund University has worked on developing a drug against preeclampsia—a serious disorder which annually affects around 9 million pregnant women worldwide and is one of the main ...

Cardiology

New approach uses magnetic beads to treat preeclampsia

Preliminary laboratory tests show that functionalized magnetic beads successfully reduced blood levels of a harmful molecule that is elevated during preeclampsia, according to new research in the American Heart Association's ...

Obstetrics & gynaecology

Preeclampsia treatment for mothers also benefits offspring

An estimated six to 15 million people in the U.S. are children born of a pregnancy complicated by preeclampsia. New research performed in rats reveals that treating preeclampsia with sildenafil citrate (Viagra) may help protect ...

Obstetrics & gynaecology

Pregnancy disorder subject of new Tulane study

An imaging technique used to detect some forms of cancer can also help detect preeclampsia in pregnancy before it becomes a life-threatening condition, a new Tulane study says.

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Pre-eclampsia

Pre-eclampsia or preeclampsia is a medical condition in which hypertension arises in pregnancy (pregnancy-induced hypertension) in association with significant amounts of protein in the urine.

Pre-eclampsia refers to a set of symptoms rather than any causative factor, and there are many different causes for the condition. It appears likely that there are substances from the placenta that can cause endothelial dysfunction in the maternal blood vessels of susceptible women. While blood pressure elevation is the most visible sign of the disease, it involves generalized damage to the maternal endothelium, kidneys, and liver, with the release of vasoconstrictive factors being secondary to the original damage.

Pre-eclampsia may develop from 20 weeks gestation (it is considered early onset before 32 weeks, which is associated with increased morbidity). Its progress differs among patients; most cases are diagnosed pre-term. Pre-eclampsia may also occur up to six weeks post-partum. Apart from Caesarean section or induction of labor (and therefore delivery of the placenta), there is no known cure. It is the most common of the dangerous pregnancy complications; it may affect both the mother and the unborn child.

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