Neuroscience

Discovery illuminates how brain cells die in prion diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form within and kill brain cells ...

Diseases, Conditions, Syndromes

Viral infections could promote neurodegeneration

Some viral diseases could possibly contribute to neurodegeneration. DZNE researchers report this in the journal Nature Communications. Their assessment is based on laboratory experiments in which they were able to show that ...

Diseases, Conditions, Syndromes

Prion diseases: New clues in the structure of prion proteins

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals. Bovine spongiform encephalopathy (BSE) or "mad cow" disease is one of the most famous ...

Diseases, Conditions, Syndromes

Naturally occurring antibodies against prion proteins found in humans

Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies. The significance is that prion proteins ...

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