For the first time, scientists have isolated a mutated prion protein that can multiply in the lab but not in living animals, according to a PLOS Pathogens study. The mutant prion provides new insights into the mechanisms ...
Nov 23, 2016
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A new model of fatal brain diseases is being developed in the fruit fly by a team led by Dr Raymond Bujdoso at the University of Cambridge, and could lead to a low cost, fast and efficient blood test to diagnose - and prevent ...
Oct 13, 2016
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Groundbreaking research from the University of Alberta has identified the structure of the infectious prion protein, the cause of "mad cow disease" or BSE, chronic wasting disease in deer and elk and Creutzfeldt-Jakob disease ...
Sep 8, 2016
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Prion diseases are deadly neurodegenerative disorders in humans and animals that are characterized by misfolded forms of prion protein (PrP). Development of effective treatments has been hampered by the lack of good experimental ...
Aug 9, 2016
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Prion diseases are fatal and incurable neurodegenerative conditions of humans and animals. Yet, how prions kill nerve cells (or neurons) remains unclear. A study published on May 26, 2016 in PLOS Pathogens describes a system ...
May 26, 2016
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Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a family of rare progressive, neurodegenerative illnesses that affect both humans and animals. TSE surveillance is important for public health and food ...
Apr 8, 2016
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Immunotherapy to ameliorate neurodegeneration by targeting brain protein aggregates with antibodies is an area of intense investigation. A study published on January 28th in PLOS Pathogens examines seemingly contradictory ...
Jan 28, 2016
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At times, to understand something well, it is useful to rebuild it from scratch. It happens with prions as well: in collaboration with the BESTA Institute in Milan, the Laboratory of Prion Biology at SISSA in Trieste assembled ...
Jan 4, 2016
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Prion diseases—incurable, ultimately fatal, transmissible neurodegenerative disorders of mammals—are believed to develop undetected in the brain over several years from infectious prion protein. In a new study, National ...
Sep 22, 2015
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For much of her adult life Valerie Sim has been fascinated by a disease very few in the world can claim to even begin to understand. Sim is one of Canada's foremost authorities on prion disease—more commonly known as bovine ...
Sep 3, 2015
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