One major challenge in cancer research is developing robust pre-clinical models for new therapies, ones that will accurately reflect a human response to a novel compound. All too often, a potential treatment that initially ...
Oct 5, 2017
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43
A major health problem in older people is age-associated osteoporosis—the thinning of bone and the loss of bone density that increases the risk of fractures. Often this is accompanied by an increase in fat cells in the ...
Sep 22, 2017
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142
As the embryonic brain develops, an incredibly complex cascade of cellular events occur, starting with progenitors - the originating cells that generate neurons and spur proper cortex development. If this cascade malfunctions ...
Sep 20, 2017
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48
How do the multiple different cell types in the blood develop? Scientists have been pursuing this question for a long time. According to the classical model, different developmental lines branch out like in a tree. The tree ...
Aug 16, 2017
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1
People with multiple sclerosis (MS) know all too well the frustration of hearing that success in treating the disease in mice had little or no effect in humans.
Aug 15, 2017
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7
In contrast to what has been previously believed, development of blood stem cells into mast cells, a type of specialised immune cell, does not depend on stem cell factor. This has been demonstrated in a new collaborative ...
Aug 10, 2017
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1
Every day, 17 million HIV-infected people around the world swallow pills that keep the virus inside them at bay.
Jul 31, 2017
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67
New research has identified the culprit behind the wiring problems in the brains of people with schizophrenia. When researchers transplanted human brain cells generated from individuals diagnosed with childhood-onset schizophrenia ...
Jul 20, 2017
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143
The ubiquitous human herpesvirus 6 (HHV-6) may play a critical role in impeding the brain's ability to repair itself in diseases like multiple sclerosis. The findings, which appear in the journal Scientific Reports, may help ...
Jul 10, 2017
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983
Scientists have made an important step in understanding the organisation of nerve cells embedded within the gut that control its function - a discovery that could give insight into the origin of common gastrointestinal diseases, ...
May 19, 2017
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