Myelodysplastic syndrome (MDS), one of the most common blood cancers, has very few treatment options. Now, researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new and promising drug target for this deadly ...
Sep 25, 2019
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Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.
Nov 27, 2018
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A first-of-its-kind oligodendrocyte in vitro model shows that human cells normally supportive of motor neuron function play an active role in amyotrophic lateral sclerosis pathogenesis – and this discovery may point the ...
Sep 27, 2016
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Scientists at the University at Buffalo have identified the single transcription factor or "master switch" that initiates the critical myelination process in the brain. The research will be published online in Proceedings ...
Jun 30, 2014
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Scientists in the United States have developed a simple and robust approach for directly reprogramming mature skin cells into immature muscle cells. By combining transient expression of a protein called MyoD and treatment ...
May 8, 2018
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Across the United States, about 2 million people are living with an amputation and another 185,000 amputations occur every year, according to the Amputee Coalition, a Washington DC-based support group. About 54% of these ...
Dec 19, 2023
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Cardiovascular diseases are the leading cause of death worldwide. As a prime example, pulmonary hypertension is especially lethal, with one-half of patients dying within three years of being diagnosed. Yale researchers have ...
Oct 8, 2015
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Around the world, hundreds of women infected with the Zika virus have given birth to children suffering from microcephaly or other brain defects, as the virus attacks key cells responsible for generating neurons and building ...
Dec 1, 2016
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A process using human stem cells can generate the cells that cover the external surface of a human heart—epicardium cells—according to a multidisciplinary team of researchers.
Jan 11, 2017
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By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic ...
Dec 24, 2020
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