Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical ...
Apr 25, 2024
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To study how Zika virus proteins hijack and disrupt host developmental pathways during infection and disease progression, Dr. Shinya Yamamoto, assistant professor at Baylor College of Medicine and principal investigator at ...
Feb 28, 2024
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The thermal environment refers to the physical surroundings as it pertains to the heat exchange of an individual and its environment. Naturally, the thermal environment also relates to comfort, or more specifically, thermal ...
Jan 30, 2024
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Treatment with datopotamab deruxtecan (Dato-DXd), a novel Trop-2 directed antibody-drug conjugate, was found to significantly improve progression-free survival in patients with metastatic non-small cell lung cancer, an improvement ...
Oct 26, 2023
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Your circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review paper published in the journal Trends in Cell Biology, researchers discuss the ...
Mar 24, 2023
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A four-drug chemotherapy regimen provided longer overall survival than a two-drug combination in a Phase 3 clinical trial for metastatic pancreatic ductal adenocarcinoma. The study is believed to be the first metastatic pancreatic ...
Jan 20, 2023
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The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of ...
Sep 13, 2022
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A novel staging framework that assesses the progression of Huntington's disease (HD), similar to the way cancer is staged 0 to 4, has been developed by UCL scientists as part of an international consortium; this 'significant' ...
Jun 16, 2022
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There's no safe way to get a close-up view of the human heart as it goes about its work: you can't just pop it out, take a look, then slot it back in. Scientists have tried different ways to get around this fundamental problem: ...
Apr 23, 2022
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The world has experienced a 59% decline in the deaths of children younger than five years since 1990. New mortality estimates indicate that the largest drop was in 2019, when global under-five deaths were reduced to 5.2 million ...
Dec 8, 2021
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