In more than half of all prostate tumors, two genes—one for a transcription factor called ERG, the other a testosterone-triggered gene called TMPRSS2—become fused together, resulting in excess ERG expression. The TMPRSS2-ERG ...
Aug 3, 2018
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The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate ...
Feb 28, 2019
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Uncovering the network of genes regulated by a crucial molecule involved in cancer called mTOR, which controls protein production inside cells, researchers at the University of California, San Francisco (UCSF) have discovered ...
Feb 22, 2012
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Researchers at the University of Michigan Comprehensive Cancer Center have discovered two cancer-spurring gene rearrangements that may trigger 5 to 7 percent of all breast cancers.
Nov 20, 2011
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(Medical Xpress)—A research team made up of representatives from several cancer research centers in the United States has found that cancers that develop in the prostate of mice may be either aggressive or sluggish depending ...
The detection and quantification of cancer-associated molecular biomarkers in body fluids, or liquid biopsies, prove minimally invasive in early cancer diagnostics. Researchers at the University of Illinois Urbana-Champaign ...
Jan 28, 2022
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Researchers at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute have uncovered for the first time the vital role a popular protein plays in the stroma, the cell-lined area outside of a prostate tumor.
Jun 25, 2013
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Hormone therapy is successful at keeping metastatic prostate cancer under control, but eventually the tumor cells become resistant to it. An unexpected potential solution has now emerged in medicines not designed to fight ...
Jun 27, 2022
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Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients. In a new article published today in Science ...
May 3, 2023
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According to new findings published in Science Translational Medicine, Cleveland Clinic researchers have identified a promising drug target for treating and preventing aggressive, drug-resistant prostate cancer.
May 26, 2021
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