Scientists have known for years that amyloid fibrils—fibrous, ropelike structures formed by closely linked protein molecules—are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play ...
Apr 20, 2022
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Specific mutations in the protein associated with Parkinson's Disease, in which just one of its 140 building blocks is altered, can make a dramatic difference to processes which may lead to the condition's onset, researchers ...
Aug 29, 2016
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Previous research has implicated fungi in chronic neurodegenerative conditions such as Alzheimer's disease, but there is limited understanding of how these common microbes could be involved in the development of these conditions.
Oct 16, 2023
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Blocking a transport pathway through the brain cells offers new prospects to prevent the development of Alzheimer's. Wim Annaert and colleagues of VIB and K.U. Leuven discovered that two main agents involved in the inception ...
Aug 22, 2011
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A new study suggests that it is possible to design drugs that can target a type of shape-shifting protein involved in Alzheimer's disease, which was previously thought to be undruggable.
Nov 4, 2020
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Today, by and large, patients receive a diagnosis of Alzheimer's only after they exhibit well-known signs of the disease, such as memory loss. By that point, the best treatment options simply slow further progression of symptoms.
Dec 5, 2022
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A new DNA vaccine when delivered to the skin prompts an immune response that produces antibodies to protect against toxic proteins associated with Alzheimer's disease - without triggering severe brain swelling that earlier ...
May 23, 2017
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Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...
Aug 14, 2019
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Scientists at The Scripps Research Institute (TSRI) have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how ...
Apr 10, 2013
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Protein aggregates have been observed in the nerve tissue of patients with Parkinson's disease which consist of individual components (monomers) of the protein α-synuclein which assemble into what are referred to as amyloid ...
Sep 3, 2019
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