Medical research

Platform precisely quantifies antigens presented on cell surfaces

Normally, the immune system is able to differentiate between healthy and abnormal cells. Peptides, fragments created by the synthesis and breakdown of proteins inside each cell, are presented on the surface as antigens and ...

Oncology & Cancer

A leap forward in research on CAR T cell therapy

In cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of the most significant recent advances in immunotherapies targeted at cancer.

Oncology & Cancer

Confining cell-killing treatments to tumors

Cytokines, small proteins released by immune cells to communicate with each other, have for some time been investigated as a potential cancer treatment.

Oncology & Cancer

Modified immune cells seek and destroy melanoma

In this issue of the Journal of Clinical Investigation, researchers led by Scott Pruitt at Duke University and Merck Research Laboratories report on a human clinical trial in which modified dendritic cells, a component of ...

Immunology

Countering atopic dermatitis immune reactions

Human leukocyte antigen (HLA)-G is a protein that interacts with specific cell receptors to inhibit immune responses. The protein is best known for its role in protecting the fetus from attack by its mother's immune system. ...

Oncology & Cancer

Researchers develop novel treatment for prostate cancer

(Medical Xpress)—The work of a team of Wake Forest researchers developing a novel drug for prostate cancer treatment is featured on the cover of the Nov. 26 issue of the Journal of Medicinal Chemistry.

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