Cancer biology: Targeting tumors with 'stapled' peptides
(Phys.org) —Designer peptides containing chemically stabilized helices emerge as a potent way to activate anti-tumor proteins inside cells.
Jul 17, 2013
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(Phys.org) —Designer peptides containing chemically stabilized helices emerge as a potent way to activate anti-tumor proteins inside cells.
Jul 17, 2013
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Even today, the lives of humans and animals are claimed by plague. A new antibody-based detection method can be used to reliably and sensitively identify plague in patient serum and other biological samples. The antibody ...
Jul 17, 2013
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Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...
May 31, 2013
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The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable ...
Apr 17, 2013
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Through a series of investigations in mice and humans, Johns Hopkins researchers have identified a protein that appears to be the target of both antidepressant drugs and electroconvulsive therapy. Results of their experiments ...
Feb 7, 2013
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Impacting approximately one-third of the U.S. population, obesity is a significant health concern for Americans. It's a risk factor for developing type 2 diabetes, heart disease, and certain forms of cancer, and now, according ...
Feb 6, 2013
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B cells can generate different 'classes' of antibodies, each of which carries a specific type of protein chain that triggers a specific downstream cascade of immune responses. Immunoglobulin M (IgM) antibodies, which are ...
Feb 1, 2013
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In their quest for new agents, pharmaceutical researchers test millions of substances all over the world. They like using color-forming reactions to identify new molecules. However, in intensively colored solutions or in ...
Dec 20, 2012
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Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients ...
Dec 12, 2012
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A new discovery from researchers at Huntsman Cancer Institute (HCI) at the University of Utah concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study ...
Nov 16, 2012
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