Palbociclib is clinically approved for use in treating breast cancer, but according to a new study, the molecular mechanism behind the drug's effectiveness is not what scientists had thought it was.
Dec 18, 2019
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University of Cincinnati researchers have found additional ways to target the molecular processes involved in activating a certain protein complex to potentially develop new therapies for a tumor-causing disorder.
Nov 11, 2019
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Rapid communication of neurons in the brain, as well as the ability to learn, fundamentally rely on neurotransmitter receptors located in the contact sites of neurons, the synapses. The most important receptors in the mammalian ...
Oct 15, 2019
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Each year, heart attacks kill almost 10 million people around the world, and more than 6 million die from stroke. A heart attack is caused by clots that block arterial blood flow. Tissues are deprived from blood-borne oxygen. ...
Oct 15, 2019
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Three researchers from the United States and Britain on Monday shared the Nobel Medicine Prize for research into how human cells sense and adapt to changing oxygen levels, opening up new strategies to fight such diseases ...
Oct 7, 2019
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A novel anticancer molecule created by researchers at The Wistar Institute showed therapeutic activity in preclinical models of various cancer types. This cell-permeable peptidomimetic was designed to disrupt a newly identified ...
Oct 3, 2019
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Beta cells in pancreatic islets produce insulin to exquisitely regulate blood glucose levels and, thus, provide energy to cells throughout the body. Loss or dysfunction of the beta cells results in diabetes, a major public ...
Sep 5, 2019
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Research shows that bacteria use hydrogen peroxide to weaken the immune system and cause pneumonia. This according to a study at Umeå University and Stockholm University, Sweden. Hydrogen peroxide is also known as a bleaching ...
Sep 2, 2019
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Schwann cells form a protective sheath around nerve fibres and ensure that nerve impulses are transmitted rapidly. If these cells are missing or damaged, severe neurological diseases may occur as a result. Researchers at ...
Aug 27, 2019
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Targeting specific areas of the measles virus polymerase, a protein complex that copies the viral genome, can effectively fight the measles virus and be used as an approach to developing new antiviral drugs to treat the serious ...
Aug 23, 2019
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