Medical research

Viral 'molecular scissor' is next COVID-19 drug target

American and Polish scientists, reporting Oct. 16 in the journal Science Advances, laid out a novel rationale for COVID-19 drug design—blocking a molecular "scissor" that the virus uses for virus production and to disable ...

Immunology

Early immune response may improve cancer immunotherapies

In a paper published in the Journal of Biological Chemistry, University of Illinois at Chicago researchers and colleagues report a new mechanism for detecting foreign material during early immune responses.

Medical research

Preventing tumor metastasis

Researchers at the Paul Scherrer Institute, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step toward the development of an agent against the metastasis of certain ...

Diseases, Conditions, Syndromes

Using crystals to unpack how viruses work

Researchers at Cardiff University have used X-ray crystallography and computer simulation to get a closer look at how viruses bind cells and cause infection.

Diseases, Conditions, Syndromes

Molecular Zika study finds possible target for tests, drugs

The molecular structure of the Zika virus as seen on x-ray crystallography revealed electrostatic differences in a key protein compared with other flaviviruses that might explain how it infects human cells, according to a ...

Medical research

3D images reveal the body's guardian against urinary infection

Researchers at Karolinska Institutet have obtained the first 3D structure of uromodulin, the building block of the unique safety net that constantly protects our urinary tract against bacterial infections. Uromodulin also ...

Medical research

Researchers uncover clues to flu's mechanisms

A flu virus acts like a Trojan horse as it attacks and infects host cells. Scientists at Rice University and Baylor College of Medicine have acquired a clearer view of the well-hidden mechanism involved.

Medical research

Unlocking a mystery of Huntington's disease in space

(Medical Xpress)—An experiment just launched into orbit by a team of Caltech researchers could be an important step toward understanding a devastating neurodegenerative disease.

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