The HIV-1 virus can neutralize cellular defenses with its viral infectivity factor (Vif). OIST researchers Prof. Matthias Wolf and Dr. Takahide Kouno together with an international team of colleagues have now determined the ...
Jul 14, 2023
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After 30 years of discouraging results in attempting to develop drugs to inhibit a mutated protein associated with some of the more challenging cancers to treat, research on RAS proteins is booming.
Jul 7, 2023
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New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. The study found that a protein known to be active in immune ...
Jul 5, 2023
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A new editorial paper titled "Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability" has been published in Oncotarget.
Jun 28, 2023
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With malaria becoming increasingly drug-resistant, a team of UCF researchers is looking to use cancer drugs to accelerate the discovery of new life-saving therapies for the disease.
Jun 21, 2023
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A research team led by Junior Associate Professor Kazuo Takayama (CiRA, Kyoto University) and Professor Kei Sato (Institute of Medical Science, The University of Tokyo) experimentally infected human keratinocytes and human ...
Jun 20, 2023
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Opioid drugs such as morphine and fentanyl are like the two-faced Roman god Janus: The kindly face delivers pain relief to millions of sufferers, while the grim face drives an opioid abuse and overdose crisis that claimed ...
May 31, 2023
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Dementia is defined as the loss of cognitive functioning—including thinking, remembering, and reasoning—and is very prevalent in Japan. Currently, the treatment satisfaction for dementia is among the lowest and no drug ...
May 29, 2023
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A new editorial paper was published in Oncoscience, titled, "UPR-induced ovarian cancer cell fusion: a mechanism favoring drug resistance?"
May 26, 2023
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A promising new stroke drug that temporarily inhibits a key protein in the brain without causing lasting harm may significantly change the future treatment of cerebral and global ischemia, according to a new study by scientists ...
May 23, 2023
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