(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Jan 22, 2013
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The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Jan 13, 2013
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Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer's disease, Amyotrophic Lateral Sclerosis and Parkinson's disease. Now, scientists from the Florida campus of ...
Jan 10, 2013
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In September 2012, the Encyclopedia of DNA Elements (ENCODE) Project Consortium, a multi-institution collaboration that included the Broad Institute, capped off nine years of research with a flurry of papers that characterized ...
Jan 7, 2013
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The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working ...
Dec 17, 2012
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VIB researchers from UGent and Vrije Universiteit Brussel , together with a team of the firm Oxyrane have developed a new technology that can lead to a more efficient and possibly also cheaper therapy for diseases such as ...
Nov 19, 2012
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Scientists for the first time have evidence showing how a widely used type of "targeted" cancer drug can be dangerous to the heart.
Nov 6, 2012
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When a person has a heart attack, portions of the heart muscle die in the next several days or even weeks if deprived of oxygen for long enough. The recovering heart slowly remodels itself, even fostering the growth of new ...
Nov 6, 2012
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An international research team led by the Spanish National Research Council (CSIC) and researchers from Kiel University revealed the atomic‐level structure of the human peptidase enzyme meprin β (beta). The study was published ...
Oct 4, 2012
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Researchers from IMIM, Hospital del Mar Medical Research Institute, have succeeded in determining the function of a new variant of enzyme IKKalpha (IKKα) to activate some of the genes taking part in the tumor progressions ...
Oct 4, 2012
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