Alzheimer's disease (AD) is a neurological condition leading to dementia that worsens with age as patients exhibit cognitive, memory, and psychological deficits. While current therapies focus on relieving these symptoms to ...
Aug 5, 2021
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Amyloid deposition is a hallmark of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). The deposition process is described as a sigmoidal curve in which the misfolded proteins assemble ...
Aug 2, 2023
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Groundbreaking research from the University of Alberta has identified the structure of the infectious prion protein, the cause of "mad cow disease" or BSE, chronic wasting disease in deer and elk and Creutzfeldt-Jakob disease ...
Sep 8, 2016
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EPFL scientists have developed ClearTau, an innovative method and platform for reconstructing aggregates of the protein Tau found in Alzheimer's disease and other neurodegenerative diseases. The breakthrough may speed up ...
Jul 4, 2023
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A study led by Guadalupe Sabio and José Jalife at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid has identified a new signaling mechanism implicated in the development of ventricular fibrillation, ...
Nov 27, 2023
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Many neurodegenerative diseases, including Alzheimer's, are characterized by tangled proteins called Tau fibrils. In a new study, MIT chemists have gained insight into how these fibrils form and identified a potential target ...
Jul 17, 2023
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A study led by the IBB-UAB has identified the molecular mechanism through which a protein carrying genetic mutations associated with limb-girdle muscular dystrophy type 1G accelerates its tendency to form amyloid fibrils ...
Jan 29, 2020
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Elongated fibres (fibrils) of the beta-amyloid protein form the typical senile plaque present in the brains of patients with Alzheimer's disease. A European research team, working in conjunction with a team from the United ...
Aug 4, 2016
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Dabigatran is one of the new oral anticoagulants which are increasingly used to prevent thrombosis. In case of an emergency (e.g. bleeding or urgent surgery), there are - despite the lack of a specific antidote - effective ...
Apr 8, 2013
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New research published in the Journal of Internal Medicine demonstrates that optogenetics—which uses light-sensitive proteins to control the activity of targeted cells—is a promising shock-free approach to treating atrial ...
Jun 21, 2023
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