Medical research

How oxygen deprivation causes cancer cells to spread

In breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. Ph.D. candidate Qiuyu ...

Genetics

A human interactome to prioritize drug discovery

Scientists at Open Targets, EMBL's European Bioinformatics Institute (EMBL-EBI), and GSK are revealing the shared basis of diseases using a map of interacting human proteins. By helping to understand how biological processes ...

Neuroscience

Targeting tau, the other protein behind Alzheimer's disease

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to ...

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