Diabetes
Metal binding important for metformin action
(HealthDay) -- The ability of metformin to bind mitochondrial copper may be essential to its mechanism of action, according to a study published online April 9 in Diabetes.
Apr 14, 2012
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Page 14 - News tagged with protein gene
Genetics
Molecular network identified underlying autism spectrum disorders
Researchers in the United States have identified a molecular network that comprises many of the genes previously shown to contribute to autism spectrum disorders. The findings provide a map of some of the crucial protein ...
Dec 30, 2014
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Oncology & Cancer
Antibody-drug conjugate shows impressive activity in patients with non-small cell lung cancer with mutation in HER2 gene
More than half of patients with non-small cell lung cancer (NSCLC) bearing a mutation in the HER2 gene had their tumors stop growing or shrink for an extended time after treatment with a drug that hitches a chemotherapy agent ...
Sep 19, 2021
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Oncology & Cancer
Mutant protein tackles DNA guardian to promote cancer development
Melbourne scientists have discovered how tumour development is driven by mutations in the most important gene in preventing cancer, p53.
Nov 7, 2018
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Medical research
Evidence of autoimmunity's origins uncovered via new approach
Autoimmune diseases are thought to be the result of mistaken identity. Immune cells on patrol, armed and ready to defend the body against invading pathogens, mistake normal human cells for infected cells and turn their weapons ...
Dec 7, 2022
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Diseases, Conditions, Syndromes
Researchers pinpoint genetic variations that might sway course of COVID-19
Researchers at Mayo Clinic's Center for Individualized Medicine have discovered key human genomic signatures that could help explain why COVID-19 is severe in some people and mild in others. After analyzing volumes of diverse ...
Jul 25, 2022
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Genetics
Studies of mutated protein in Lou Gehrig's disease reveal new paths for drug discovery
Several genes have been linked to ALS, with one of the most recent called FUS. Two new studies in PLoS Biology, one from the University of Pennsylvania School of Medicine, and the other from colleagues at Brandeis University, ...
Apr 26, 2011
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Medical research
Study demonstrates potential of new gene vector to broaden treatment of eye diseases
Inspired by earlier successes using gene therapy to correct an inherited type of blindness, investigators from the Perelman School of Medicine at the University of Pennsylvania, are poised to extend their approach to other ...
Jun 22, 2011
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Immunology
Scientists reveal new cystic fibrosis treatments work best in inflamed airways
A new UNC School of Medicine study shows that two cystic fibrosis (CF) drugs aimed at correcting the defected CFTR protein seem to be more effective when a patient's airway is inflamed. This is the first study to evaluate ...
Oct 11, 2018
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Medical research
Study finds new, unexpected mechanism of cancer cell spread
A surprising finding from USC reveals key details about how cancer cells metastasize and suggests new therapeutic approaches for halting their spread.
Jul 24, 2023
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