Medical research

Retooling small molecule kinase inhibitors for SARS-CoV-2

Researchers from Hefei University of Technology in China have recently published an exhaustive review in the Journal of Medicinal Chemistry on emerging roles of small kinase inhibitors in the treatment of diseases. In contrast ...

Medications

Cancer drugs show potential in fight against malaria

With malaria becoming increasingly drug-resistant, a team of UCF researchers is looking to use cancer drugs to accelerate the discovery of new life-saving therapies for the disease.

Medical research

Potential COVID-19 treatment identified

A collaboration among scientists from UCLA and other universities in California, Delaware and Germany, as well as a German pharmaceutical company, has singled out a compound that shows promise for treating SARS-CoV-2, the ...

Oncology & Cancer

New drug combination could be more effective against melanoma

A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient.

Oncology & Cancer

Scientists to improve cancer treatment effectiveness

Together with researchers from the University of Nantes and the University of Reims Champagne-Ardenne in France, experts from the National Research Nuclear University MEPhI have recently developed a quantum dot-based microarray ...

Oncology & Cancer

Old drug may have new tricks for fighting cancer

In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude ...

Medical research

New computational method exploits the polypharmacology of drugs

(Medical Xpress)—If life were simple, a disease could be treated with one drug that hits one molecular target, like striking a piano key. Instead, researchers wrestle with the fact that most drugs hit multiple targets in ...

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