In a rare but serious complication of cancer, the body's own immune system can start attacking the brain, causing rapid-onset memory loss and cognitive deficits. What triggers this sudden biological civil war was largely ...
Jan 31, 2024
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A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly reduced circulating transthyretin (TTR) protein levels in patients with ATTR amyloid cardiomyopathy, a progressive and fatal ...
Nov 7, 2022
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A new study shows that total RPE65 protein levels in mice with autosomal dominant retinitis pigmentosa were doubled following subretinal delivery of adeno-associated virus (AAV)-RPE65 gene supplementation. The study is published ...
May 23, 2023
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Scientists from the University of Luxembourg together with researchers from the Integrated Biobank of Luxembourg (IBBL) and the Luxembourg Institute of Health (LIH) have recently demonstrated the mechanisms by which low oxygen ...
Dec 17, 2019
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Blood levels of an immunity-related protein, galectin-1, in patients with newly diagnosed Hodgkin lymphoma reflected the extent of their cancer and correlated with other predictors of outcome, scientists reported at the American ...
Dec 10, 2012
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Predictive mathematical models of signalling pathways are powerful biological tools that could be used for drug development. Using a similar approach, European scientists developed a computational model for answering research ...
Aug 30, 2012
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A new understanding of what takes place on the cellular level during the development of neurodegenerative diseases, such as Parkinson's, Alzheimer's, ALS and Huntington's diseases, offers promise towards possible new strategies ...
Dec 6, 2012
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Scientists may be able to better predict which patients with colorectal cancer will respond to chemotherapy using a new mathematical model that measures the amount of stress required for a cancer cell to die without harming ...
Jan 17, 2013
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Genetically raised levels of C-reactive protein (CRP, an inflammatory protein) are associated with protection against schizophrenia, according to a Mendelian randomization study published this week in PLOS Medicine. The study, ...
Jun 21, 2016
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A group of UO biologists has developed a promising new model to study how underlying conditions exacerbate the health issues caused by COVID-19.
Jun 15, 2021
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