Diseases, Conditions, Syndromes

Adding clinical variables improves accuracy of lung allocation score

Implemented back in 2005, the lung allocation score is used to prioritize patients awaiting lung transplants in the United States. Sicker transplant candidates have a higher calculated score and are placed at the top of the ...

Diseases, Conditions, Syndromes

Protein linked to cancer growth drives deadly lung disease

A protein associated with cancer growth appears to drive the deadly lung disease known as idiopathic pulmonary fibrosis, according to new research from Cedars-Sinai. The discovery, made in laboratory mice and human tissue ...

Diseases, Conditions, Syndromes

ATS publishes new clinical guideline on home oxygen for children

The American Thoracic Society has developed a new clinical practice guideline for home oxygen therapy for children. The guideline appears in the Feb. 1 edition of the Society's American Journal of Respiratory and Critical ...

Diseases, Conditions, Syndromes

Infinite hug mechanism may be key to lung fibrosis

Researchers have long known that fibrosis – scarred tissue and organs – is caused by a wound healing mechanism that goes awry beyond normal wound repair. Now, a group of researchers at the University of Toronto's Faculty ...

Immunology

Life-threatening lung disease averted in experimental models

Idiopathic pulmonary fibrosis (IPF) is a fatal condition that leaves lung tissue permanently scarred and leads to the decline and eventual failure of the respiratory system. For those diagnosed with the disease, treatment ...

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Interstitial lung disease

Interstitial lung disease (ILD), also known as diffuse parenchymal lung disease (DPLD), refers to a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs). It concerns alveolar epithelium, pulmonary capillary endothelium, basement membrane, perivascular and perilymphatic tissues.

The term ILD is used to distinguish these diseases from obstructive airways diseases.

Most types of ILD involve fibrosis, but this is not essential. The term "pulmonary fibrosis" is no longer considered a synonym. Idiopathic pulmonary fibrosis is one form of "interstitial lung disease".

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