Diseases, Conditions, Syndromes

A genetic variation may increase tuberculosis susceptibility

Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin—a peptide involved in inflammation, immunity, and control of iron levels—is associated with greater susceptibility to ...

Diseases, Conditions, Syndromes

New trials offer hope for TB treatment

Researchers at the University of St Andrews are one step closer to finding a shorter, more effective treatment for TB, according to a new paper published by The Lancet Infectious Diseases.

Diseases, Conditions, Syndromes

Possible breakthrough in tuberculosis research on the horizon

"New weapon in fight against the deadliest disease! Medicine can be used to treat existing illness and prevent reoccurrence." These headlines were published 125 years ago and shook up not only the world of science and medicine, ...

Diseases, Conditions, Syndromes

Clinical trials of VPM1002 as a tuberculosis vaccine in newborns

The only tuberculosis vaccine currently approved, the Bacillus Calmette-Guérin (BCG) vaccine, protects children from the most severe forms of the disease in most cases but does not provide protection against the most common ...

Diseases, Conditions, Syndromes

Characteristics of tuberculosis source cases identified

(HealthDay)—In 26 U.S. tuberculosis outbreaks the initial source case-patients had long incubation periods and were characterized by substance abuse, incarceration, and homelessness, according to a study published in the ...

Diseases, Conditions, Syndromes

New whole blood assay may help overcome roadblocks to TB eradication

One of the roadblocks to the eradication of tuberculosis (TB) is the difficulty in identifying patients with latent TB infections (LTBI). Neither the tuberculin skin test (TST) nor interferon-gamma release assays (IGRAs) ...

Diseases, Conditions, Syndromes

ICAAC: Moxifloxacin regimens are not noninferior for TB

(HealthDay)—For patients with uncomplicated, smear-positive pulmonary tuberculosis, moxifloxacin-containing regimens over four months are not noninferior to a control regimen, according to a study published online Sept. ...

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