Medical research

Is the first cure for advanced rabies near?

Rabies virus is incurable and almost always fatal once it has invaded the central nervous system, with the victim doomed to suffer a horrible death.

Neuroscience

'Gut sense' is hardwired, not hormonal

If you've ever felt nauseous before an important presentation, or foggy after a big meal, then you know the power of the gut-brain connection.

Diseases, Conditions, Syndromes

Better understanding of diseases devastating African communities

While high-profile diseases such as malaria and tuberculosis tend to take the lion's share of both publicity and funding, a number of neglected diseases, transmissible between animals and humans (zoonoses), continue to devastate ...

Diseases, Conditions, Syndromes

Scientists crack rabies virus weaponry

Researchers have found a way to stop the rabies virus shutting down the body's immune defence against it. In doing so they have solved a key scientific puzzle and have laid the foundation for the development of new anti-rabies ...

Diseases, Conditions, Syndromes

New rabies virus discovered in Tanzania

(Medical Xpress) -- A new type of rabies virus has been discovered in Tanzania by scientists from the University of Glasgow and the Animal Health and Veterinary Laboratories Agency (AHVLA).

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Rabies

Rabies (pronounced /ˈreɪbiːz/. From Latin: rabies) is a viral neuroinvasive disease that causes acute encephalitis (inflammation of the brain) in warm-blooded animals. It is zoonotic (i.e. transmitted by animals), most commonly by a bite from an infected animal but occasionally by other forms of contact. Generally fatal if left untreated, it is a significant killer of livestock in some countries.

The rabies virus travels to the brain by following the peripheral nerves. The incubation period of the disease depends on how far the virus must travel to reach the central nervous system, usually taking a few months. Once the infection reaches the central nervous system and symptoms begin to show, the untreated infection is usually fatal within days.

Early-stage symptoms of rabies are malaise, headache and fever, later progressing to more serious ones, including acute pain, violent movements, uncontrolled excitement, depression and inability to swallow water. Finally, the patient may experience periods of mania and lethargy, followed by coma. The primary cause of death is usually respiratory insufficiency.

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