Researchers have developed an industry-standard tool to facilitate drug development and translational research in collaboration between labs at Karolinska Institutet and the Gygi Lab at Harvard Medical School. Their results ...
Aug 14, 2024
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Myocardial infarction (MI) is a deadly disease. It can cause serious myocardial ischemic necrosis due to coronary occlusion. The most effective treatment for MI in clinic is reperfusion, e.g., interventional or thrombolytic ...
Jan 9, 2024
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There is a growing body of evidence that iron in the brain may play a role in Alzheimer's disease. Lending weight to that idea, a new imaging probe has for the first time shown that in the same regions of the brain where ...
Apr 19, 2023
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Three-dimensional (3D) culturing approaches help probe cancer stem-like cells (CSCs)-associated traits, chemoresistance, and cellular heterogeneity ex vivo. For instance, the culture of organoid-driven clinical cancer specimens ...
Oct 7, 2021
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Organoids are tiny three-dimensional cellular assemblies that are grown in a laboratory from tissue-specific cells. They are particularly interesting to biologists because of their ability to mimic the characteristics of ...
Mar 22, 2021
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Many heart diseases are linked to oxidative stress, an overabundance of reactive oxygen species. The body reacts to reduce oxidative stress—where the redox teeter-totter has gone too far up—through production of endogenous ...
May 14, 2020
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Lung cancer is the number one cause of cancer-related deaths in the United States, with squamous cell lung cancer (SCC) being one of the common types. Despite improved knowledge of the molecular alterations in SCC, little ...
Aug 8, 2019
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Chemical changes in brain cells caused by disturbances in the body's day-night cycle may be a key underlying cause of the learning and memory loss associated with Alzheimer's disease, according to a University of California, ...
Oct 28, 2015
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(Medical Xpress)—When something bad happens to otherwise healthy neurons it's easy to blame the usual suspects—the mitochondria. In some cases the nucleus might be the one at fault, as in a de novo mutation in a critical ...
The prestigious journal Proceedings of the National Academy of Sciences of the United States of America this week published an article by a research team led by University of Delaware biochemist Sharon Rozovsky, examining ...
Apr 28, 2014
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