Oncology & Cancer

Cancer: A mutation that breaks gene interplay in 3-D

Inside cells DNA is tightly wrapped around proteins and packed in a complex, 3-D structure called chromatin. Chromatin not only protects genetic material from damage, but also organizes the entire genome by regulating the ...

Neuroscience

Nature versus nurture and addiction

The progressive understanding of addiction as a disease rather than a choice has opened the door to better treatment and research, but there are aspects of addiction that make it uniquely difficult to treat.

Oncology & Cancer

Study identifies link between DNA-protein binding, cancer onset

Researchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers ...

Immunology

Repeated interferon stimulation creates innate immune memory

Mammalian cells seem to be able to memorize anti-viral stimulation at the level of DNA-packaging molecules, enabling faster and greater activation of anti-viral genes in subsequent stimulations, according to a study conducted ...

Genetics

Genes that regulate how much we dream

Sleep is known to re-energize animals and consolidate their memories. Rapid eye movement (REM) sleep, a mysterious stage of sleep in which animals dream, is known to play an important role in maintaining a healthy mental ...

Genetics

Research reveals gene regulation can be digital and stochastic

Every cell in our body has the same set of genes, or genome, and can potentially become any type of cell. During development, the epigenome mediates the process that leads a cell to become a skin cell or a neuron, for instance. ...

Immunology

How a thieving transcription factor dominates the genome

One powerful DNA-binding protein, the transcription factor PU.1, steals away other transcription factors and recruits them for its own purposes, effectively dominating gene regulation in developing immune cells, according ...

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