A new technique for pinpointing the exact DNA regions that impact gene regulation lays the groundwork for identifying new drug targets and for developing diagnostics to predict disease risk, A*STAR scientists report.
Jan 6, 2016
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The patients have single short fingers (metacarpals) and toes (metatarsals) and can be restricted in growth due to a shortened skeleton. This hereditary disease is called brachydactyly type E (Greek for short fingers). Three ...
Nov 5, 2012
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A recent study led by Gergely Lukacs, a professor at McGill University's Faculty of Medicine, Department of Physiology, and published in the January issue of Cell, has shown that restoring normal function to the mutant gene ...
Mar 12, 2012
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St. Jude Children's Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such as sickle cell disease and ...
May 6, 2021
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Children exposed to air pollution, such as wildfire smoke and car exhaust, for as little as one day may be doomed to higher rates of heart disease and other ailments in adulthood, according to a new Stanford-led study. The ...
Feb 22, 2021
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As cell biologists at Johannes Gutenberg University Mainz in Germany have discovered, nerve cells can enlist the aid of mini-vesicles of neighboring glial cells to defend themselves against stress and other potentially detrimental ...
Oct 6, 2014
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Researchers at Columbia University have found a molecule that is responsible for arousing dormant cells from breast cancer and nudging them to create metastases. Silencing this molecule, called Malat1, in mice with breast ...
Feb 19, 2024
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RIKEN geneticists have developed a tool that can quickly and accurately analyze variants in mobile genetic elements, commonly known as "jumping genes." This promises to shed light on the role such variants play in disease.
Oct 31, 2023
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Rett syndrome is a rare neurodevelopmental disorder for which there is currently no cure or good therapy. It causes severe physical and cognitive symptoms, including many that overlap with autism spectrum disorder.
May 2, 2024
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Genetics researchers at the University of Adelaide have solved a 40-year mystery for a family beset by a rare intellectual disability – and they've discovered something new about the causes of intellectual disability in ...
Oct 25, 2012
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