Immunology

Regulating the regulators of the immune system

Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer cells.

Oncology & Cancer

Advanced prostate cancer antibody drug shows success in pet dogs

Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research. In the first use of canines in an advanced prostate cancer study, ...

Immunology

Discovering a new B cell that tempers autoimmunity

Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation. Infusions of purified IL-27 regulatory ...

Oncology & Cancer

How immune cells in the tumor microenvironment make things worse

Cells from the immune system called CD4+ regulatory T cells, or simply Treg, are linked to tumor prognosis: the more Treg cells present in a tumor, the worst the prognosis. We know from previous research studies that Treg ...

HIV & AIDS

Oral health in HIV+ population

Pushpa Pandiyan, associate professor of biological sciences in the School of Dental Medicine, and a team of researchers have been working to discover the cause behind residual systemic inflammation and dysfunction of the ...

HIV & AIDS

Investigating mechanisms behind early HIV-1 infection

Northwestern Medicine investigators have discovered that a microtubule regulatory protein inhibits early HIV type 1 (HIV-1) infection, according to findings published in Proceedings of the National Academy of Sciences.

page 9 from 40