A single-letter change in the genetic code is enough to generate blond hair in humans, in dramatic contrast to our dark-haired ancestors. A new analysis by Howard Hughes Medical Institute (HHMI) scientists has pinpointed ...
Jun 1, 2014
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Scientists from The Australian National University (ANU) have discovered a gene mutation is responsible for causing psoriasis—a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches ...
Mar 25, 2024
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Much like ripples on the water can betray powerful currents below the surface, small changes in our bodies can sometimes be an indicator of a serious condition. Now, researchers from Japan say that cells in the blood may ...
Jan 11, 2024
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A highly aggressive common form of leukemia which is activated by mutations in signaling molecules is maintained by a web of regulatory proteins downstream of these signals.
Dec 20, 2023
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Scientists at St. Jude Children's Research Hospital described the gene regulatory networks contributing to differences between subtypes of the most common childhood cancer, acute lymphoblastic leukemia (ALL). The work examined ...
Nov 20, 2023
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Nearly half of the human genome is composed of transposable elements, which are sequences of DNA that are able to replicate and relocate in the genome. Previously, transposable elements have been considered "junk" DNA in ...
Oct 2, 2023
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Researchers at the Centre for Genomic Regulation (CRG) and Imperial College London have found a switch that regulates the activity of a gene that causes diabetes. The findings, published in Nature Cell Biology, highlight ...
Oct 27, 2022
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A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.
Oct 26, 2022
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National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's ...
Oct 7, 2022
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Mild, persistent inflammation in tissue is considered one of the biological hallmarks of the aging process in humans—and at the same time is a risk factor for diseases such as Alzheimer's or cancer. Prof. Francesco Neri ...
Sep 22, 2022
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