Genetics

Genetic controller prepares immune system for diverse threats

An army of immune cells circulates the human body to protect against its potential foes—viruses, bacteria, cancer cells, and other invaders. Because the immune system cannot know what to expect, it must be prepared to ...

Medical research

Project aims to achieve cell-based heart repair

Chronic heart failure—also known as cardiac insufficiency in medicine—is the most common reason for hospital admissions and one of the most frequent causes of death in the western world. In Germany alone, 4 million people ...

Oncology & Cancer

Researchers identify new target for cancer immunotherapy

Massachusetts General Hospital investigators have found new evidence that the tumor necrosis factor receptor type II (TNFR2) may be a major target for immuno-oncology treatments, which induce a patient's immune system to ...

Immunology

Researchers discover how immune cells resist radiation treatment

Researchers at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai have discovered a key mechanism by which radiation treatment (radiotherapy) fails to completely destroy tumors. And, in the journal ...

Arthritis & Rheumatism

Vitamin D supplements may benefit lupus patients

A new clinical study published in BioMedCentral's open access journal Arthritis Research and Therapy provides preliminary evidence that vitamin D supplementation could be considered an immunomodulatory agent for systemic ...

Immunology

Study identifies two different regulatory T cell populations

A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children's Hospital of Philadelphia (CHOP). ...

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