Immunology

Inhibition by an immunostimulator

The receptor CD27 found on the cell surface of certain types of immune cells is required for the production of so-called regulatory T cells in the thymus, that limit the development of atherosclerotic plaques.

Immunology

Researchers release the brakes on the immune system

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural "brakes" in the immune defense mechanism that normally prevent an excessive immune response. Researchers at the ...

Neuroscience

Gene immunotherapy protects against multiple sclerosis in mice

A potent and long-lasting gene immunotherapy approach prevents and reverses symptoms of multiple sclerosis in mice, according to a study published September 21st in the journal Molecular Therapy. Multiple sclerosis is an ...

Diabetes

Could modifying gut microbes prevent or delay type 1 diabetes?

Autoimmune diseases such as type 1 diabetes are controlled by our genes. While researchers are eager to find out what other factors could contribute to this disease, a new study published by Yale researchers provides direct ...

Immunology

Allergies? Exhausted regulatory T cells may play a role

Researchers have evidence that the specialized T cells responsible for maintaining a balanced immune response are vulnerable to exhaustion that disrupts normal functioning and may even contribute to allergic reactions. St. ...

Immunology

Study reveals how to reprogram cells in our immune system

When the immune system is imbalanced, either due to overly-active cells or cells that suppress its function, it causes a wide range of diseases, from psoriasis to cancer. By manipulating the function of certain immune cells, ...

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