New research has found a subset of our immune cells (called regulatory T cells) that are highly abundant in the tumor microenvironment and are particularly good at suppressing the anticancer immune response. In two independent ...
Nov 15, 2016
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In people with chronic infections or cancer, disease-fighting T cells tend to behave like an overworked militia - wheezing, ill-prepared, tentative - in a state of "exhaustion" that allows disease to persist. In a paper posted ...
Oct 27, 2016
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Researchers at the University of Cambridge have taken the first step towards developing a new form of treatment for type 1 diabetes which, if successful, could mean an end to the regular insulin injections endured by people ...
Oct 11, 2016
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ETH researchers have discovered that certain cells in the immune system suppress the development of lymphedema. Anti-inflammatory therapies could therefore be the key to treating this previously incurable condition.
Oct 11, 2016
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A Ludwig Cancer Research study published online September 5th in Nature Immunology illuminates a key requirement for the function of regulatory T cells—immune cells that play a critical role in many biological processes, ...
Sep 22, 2016
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Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants. The researchers describe the ...
Aug 15, 2016
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In atherosclerosis, the buildup of cholesterol deposits in arteries poses a major risk for cardiovascular diseases like heart attack and stroke. As cholesterol accumulates, it triggers an inflammatory response that recruits ...
Aug 2, 2016
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Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection—and all that separates us from these foreign ...
Jun 13, 2016
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Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn't just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid ...
Jun 6, 2016
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Therapies based on natural immune system cells hold great potential for treating autoimmune diseases and reducing the number of graft rejections. However, harvesting enough cells from healthy donors in their pure, uncontaminated ...
May 6, 2016
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