Cells from the immune system called CD4+ regulatory T cells, or simply Treg, are linked to tumor prognosis: the more Treg cells present in a tumor, the worst the prognosis. We know from previous research studies that Treg ...
Nov 29, 2021
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Activating the immune system to battle infections or cancers depends on more than detecting the threat. The immune system must also detect whether its cells have sufficient nutrients to fuel the immune response.
Nov 19, 2021
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Pushpa Pandiyan, associate professor of biological sciences in the School of Dental Medicine, and a team of researchers have been working to discover the cause behind residual systemic inflammation and dysfunction of the ...
Nov 5, 2021
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A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold" tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can ...
Sep 10, 2021
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A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, ...
Aug 11, 2021
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Research in mice, published today in Science Immunology by researchers at the Babraham Institute, UK and VIB-KU Leuven, Belgium, provides two solutions with potential to overcome a key clinical limitation of immune cell therapies. ...
Jul 23, 2021
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You can't make a banana split without bananas. And you can't generate stable regulatory T cells without Vitamin C or enzymes called TET proteins, it appears.
Jul 21, 2021
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In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a ...
Jul 20, 2021
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When we are exposed to a pathogen, the immune system's B cells swarm to our lymph nodes, spleens, and tonsils. There, those cells mutate in germinal centers—microscopic boot camps that rush the B cells through volleys of ...
Jul 16, 2021
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While vaccines are doing a remarkable job of slowing the COVID-19 pandemic, infected people can still die from severe illness and new medications to treat them have been slow to arise. What kills these patients in the end ...
Jul 1, 2021
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