Genetics
Huntington's disease genetic mutations expand throughout life
The region of DNA associated with Huntington's disease has been shown to grow throughout life and contribute towards disease progression.
Oct 10, 2019
0
6
Page 3 - News tagged with repair genes
Oncology & Cancer
Testing for inherited mutations could benefit men with advanced prostate cancer
Inherited mutations in genes that function to repair DNA may contribute to metastatic prostate cancer more than previously recognized, according to a study out today in the New England Journal of Medicine. Though infrequent ...
Jul 6, 2016
0
3
Oncology & Cancer
World-first cancer drugs could work in larger group of patients
A pioneering class of drugs that target cancers with mutations in the BRCA breast cancer genes could also work against tumours with another type of genetic fault, a new study suggests.
Mar 19, 2015
0
23
Oncology & Cancer
Progressive telomere shortening characterizes familial breast cancer patients
Telomeres, the complex structures that protect the end of chromosomes, of peripheral blood cells are significantly shorter in patients with familial breast cancer than in the general population. Results of the study carried ...
Jul 29, 2011
0
0
Medical research
Scientists uncover DNA 'shield' with crucial roles in normal cell division
Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.
Jul 18, 2018
0
46
Genetics
Gene therapy research shows potential for repairing damage caused by glaucoma and dementia
Scientists at the University of Cambridge have shown in animal studies that gene therapy may help repair some of the damage caused in chronic neurodegenerative conditions such as glaucoma and dementia. Their approach demonstrates ...
Mar 31, 2021
0
81
Oncology & Cancer
Scientists discover gene linked to breast and ovarian cancer
(Medical Xpress)—A team of researchers led by the Institute of Cancer Research, London, have found that rare mutations in a gene called PPM1D are linked to an increased risk of breast and ovarian cancer. The mutations are ...
Dec 17, 2012
0
0
Genetics
New tool improves the search for genes that cause diseases
A new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease. The tool, described in a new paper published January 26, 2024, in Nature Genetics, ...
Jan 26, 2024
0
45
Medical research
Researchers review muscular dystrophy therapies
Leading muscular dystrophy researcher Dean Burkin, of the University of Nevada School of Medicine summarizes the impact of a new protein therapeutic, MG53, for the treatment of Duchenne muscular dystrophy in an article published ...
Jun 22, 2012
0
0
Genetics
Study finds crucial step in DNA repair
Scientists at Washington State University have identified a crucial step in DNA repair that could lead to targeted gene therapy for hereditary diseases such as "children of the moon" and a common form of colon cancer.
Aug 18, 2014
0
0
