Genetics

Gene controls three different diseases

An international research consortium led by the Universitat Autònoma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending ...

Cardiology

Gene therapy may activate stem cells in heart failure patients

(HealthDay)—Delivery of an SDF-1 encoding plasmid (JVS-100) acts a homing signal for stem cells and improves clinical status in patients with symptomatic heart failure due to ischemic cardiomyopathy (IsCM), according to ...

Oncology & Cancer

Cancer biology: Keeping bad company

The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of tumorigenesis. ...

Medical research

Oxidative DNA damage repair

Oxidative stress damages DNA. Researchers in the Vetsuisse Faculty have now decoded the mechanism that repairs DNA damaged in this way. This repair mechanism could lead to less invasive approaches in cancer therapy and contribute ...

Medical research

Molecular corkscrew

Scientists from the universities of Zurich and Duisburg-Essen have discovered a specific function of the protein p97/VCP. They demonstrate that the protein repairs DNA breaks like a corkscrew, a repair mechanism that could ...

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