Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...
Apr 23, 2013
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Treatments that harness the immune system to fight cancer have greatly improved outcomes for some people with cancer. Scientists are learning more about why some people respond much better than others to these drugs.
Dec 1, 2020
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(Medical Xpress)—For decades, scientists have searched for treatments for myopathies – genetic muscular diseases such as muscular dystrophy and ALS, also called Lou Gehrig's disease. Now, an interdisciplinary team of ...
Nov 4, 2013
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Scientists at The University of Texas MD Anderson Cancer Center may have discovered why some brain cancer patients develop resistance to standard treatments including radiation and the chemotherapy agent temozolomide.
Mar 2, 2015
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In matters of the fundamental molecular biology of aging, we mammals are not so different from tiny C. elegans worms. Some of the biggest differences only serve to make them convenient research models. But one distinction ...
Feb 22, 2016
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Many chemotherapy drugs work by damaging cancer cells' DNA so severely that the cells are forced to commit cellular suicide. However, these drugs don't work for all patients: If cells can repair the DNA damage, they may survive ...
Nov 2, 2016
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A team of Georgia State University researchers is fighting cancers using a combination of therapies and recently found ways that radiation could maximize responses to novel immune-based therapeutic approaches to fight cancer.
Feb 2, 2016
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In current health lore, antioxidants are all the rage, as "everybody knows" that reducing the amount of "reactive oxygen species"—cell-damaging molecules that are byproducts of cellular metabolism—is critical to staying ...
Jun 14, 2013
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The busy world inside a cell is directed by its DNA blueprint. When the blueprints are altered, cells can sicken, die or become cancerous. To keep DNA in working order, cells have ways to detect and mend damaged DNA.
Nov 8, 2017
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Vanderbilt researchers have developed an active machine learning approach to predict the effects of tumor variants of unknown significance, or VUS, on sensitivity to chemotherapy. VUS, mutated bits of DNA with unknown impacts ...
Aug 9, 2022
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