In a prospective phase II study that involved patients with mismatch repair–deficient locally advanced rectal cancer, treatment with neoadjuvant single-agent, PD1 inhibitor dostarlimab resulted in a clinical complete response—as ...
Jun 9, 2022
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As an approach to personalized medicine, a new Nature Communications study proposes that "mutational footprints" of DNA repair are a promising predictive genetic marker for determining which tumors will respond to certain ...
May 26, 2022
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A new way in which cancer cells can repair DNA damage has been discovered by researchers at the University of Birmingham.
May 19, 2022
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Instead of relying on the cell's repair mechanisms, the vaccinia virus MacGyvers a tool for DNA repair from one that it already uses to copy DNA, reports a team of researchers at the Medical University of South Carolina (MUSC) ...
May 17, 2022
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Cigarette smoking is overwhelmingly the main cause of lung cancer, yet only a minority of smokers develop the disease. A study led by scientists at Albert Einstein College of Medicine and published online today in Nature ...
Apr 11, 2022
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A Florida State University College of Medicine researcher has made a discovery that alters our understanding of how the body's DNA repair process works and may lead to new chemotherapy treatments for cancer and other disorders.
Mar 8, 2022
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A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that could eventually give rise to better cancer treatments. The study is published ...
Feb 23, 2022
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New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair. The findings could improve our understanding of the processes used by cells to repair tissues, ...
Feb 10, 2022
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Researchers at the Francis Crick Institute have pieced together genetic and molecular changes that lead to a rare progressive neurodegenerative condition called ataxia with oculomotor apraxia 2.
Jan 20, 2022
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151
Researchers at Baylor College of Medicine have uncovered a more detailed picture of how the intestinal epithelium—the lining of the intestines—heals itself after infection with rotavirus. A meticulous single-cell analytical ...
Nov 3, 2021
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