Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide. Despite the availability of a safe and effective vaccine for over 40 years, HBV remains a leading ...
Nov 13, 2023
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In 2022, an estimated 7,000 Canadians were diagnosed with leukemia, a term used to define cancer of the blood cells. Of that 7,000, it is estimated that nearly half will face mortality. University of Saskatchewan (USask) ...
Feb 7, 2023
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Ludwig Maximilian University of Munich researchers have shown that derivatives of a known drug inhibit the replication of a pathogenic coronavirus in cultured human cells. These compounds can now serve as a basis for the ...
Mar 18, 2014
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St. Jude Children's Research Hospital scientists have rewritten the job description of the protein TopBP1 after demonstrating that it guards early brain cells from DNA damage. Such damage might foreshadow later problems, ...
Apr 23, 2012
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SARS-CoV-2 depends on the broadly antiviral interferon-induced human transmembrane proteins (IFITMs), to enter human cells and replicate inside them, according to research published this week in the Journal of Virology, ...
May 11, 2022
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Respiratory infections can be severe—even deadly—in some individuals, but not in others. Scientists at St. Jude Children's Research Hospital, the Peter Doherty Institute for Infection and Immunity and other collaborators ...
Aug 12, 2024
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Researchers at The Jackson Laboratory have created a panel of genetically diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection. Together with collaborators at NIH's Rocky Mountain ...
Aug 11, 2023
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There is strong evidence that the protein complex APC/C may function as a tumor suppressor in multiple cancers including lymphoma, colorectal and breast cancer, and now melanoma. A new study has revealed that a genetic mutation ...
Sep 2, 2015
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Almost one percent of all American babies are born with malformed hearts. Heart abnormalities are at once the most common and most deadly type of birth defect in the U.S.
Apr 10, 2019
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A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. The findings, ...
Jul 20, 2016
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