Diseases, Conditions, Syndromes

Study reveals OLAH enzyme underpins lethal respiratory viral disease

Respiratory infections can be severe—even deadly—in some individuals, but not in others. Scientists at St. Jude Children's Research Hospital, the Peter Doherty Institute for Infection and Immunity and other collaborators ...

Oncology & Cancer

Feedback loop promotes cancer cells' adaption to molecular stress

Investigators from the laboratory of Marc Mendillo, Ph.D., associate professor of Biochemistry and Molecular Genetics, have discovered new cellular regulators of a cancer cell transcription factor linked to cancer resilience ...

Oncology & Cancer

Tpex cells: A game-changer in targeted tumor immunotherapy

Progenitor exhausted CD8+ T (Tpex) cells have emerged as a pivotal component in tumor immunotherapy due to their unique ability to self-renew and rapidly proliferate. These cells have shown promise in expanding and differentiating ...

Diseases, Conditions, Syndromes

WHO calls emergency committee on mpox spread

The World Health Organization's chief announced Wednesday he was urgently convening an expert committee to advise on whether the growing mpox outbreak in Africa should be declared an international emergency.

Oncology & Cancer

Circular RNAs—the new frontier in cancer research

Unraveling the complexities of circular RNAs (circRNAs) in cancer biology has positioned scientists on the cusp of revolutionary breakthroughs in the diagnosis and treatment of cancer.

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