Ophthalmology

Simulating new treatment for retinal degeneration

For a few years now optogenetics has been seen as a very promising therapy for progressive blindness, for example when it is a result of retinal degeneration. In order to further develop this therapeutic approach, Marion ...

Genetics

Delivering large genes to the retina is problematic

A new study has shown that a commonly used vector for large gene transfer can successfully deliver genes to retinal cells in the laboratory, but when injected subretinally into rats it provokes a robust and acute inflammatory ...

Ophthalmology

Suitable marker for retina morphology across species

Outer retinal band (ORB) integrity and outer retinal thickness as they appear on OCT (Optical Coherence Tomography) have been studied extensively due to their diagnostic value. They are predictive of visual outcome in many ...

Ophthalmology

New cell models for ocular drug discovery

Researchers at the University of Eastern Finland have developed two new cell models that can open up new avenues for ocular drug discovery. The new cell models are continuously growing retinal pigment epithelial cells, which ...

Ophthalmology

GARP2 accelerates retinal degeneration in a mouse model

In the retina of the eye, rod and cone cells turn light into electrical signals, the first step toward human vision. University of Alabama at Birmingham researchers are studying rod cell proteins GARP1 and GARP2 to learn ...

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