Glaucoma, the second leading cause of blindness, usually stems from elevated eye pressure, which in turn damages and destroys specialized neurons in the eye known as retinal ganglion cells. To better understand these cellular ...
Feb 11, 2015
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A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, ...
Jun 2, 2022
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Macquarie Medical School researchers have developed a technique for a gene therapy that could help treat the world's leading cause of irreversible blindness. The findings are published in the journal Molecular Therapy.
Jun 27, 2023
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Researchers at Universitätsmedizin Berlin and the Max Planck Institute for Biological Intelligence (currently in the process of being established) have revealed the precise connections between sensory neurons inside the ...
Sep 12, 2022
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When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report.
Feb 11, 2019
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Northwestern Medicine scientists have discovered a cell in the retina that may cause myopia when it dysfunctions. The dysfunction may be linked to the amount of time a child spends indoors and away from natural light.
Feb 6, 2017
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A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.
Mar 1, 2022
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The human brain has 100 billion neurons, connected to each other in networks that allow us to interpret the world around us, plan for the future, and control our actions and movements. MIT neuroscientist Sebastian Seung wants ...
Aug 7, 2013
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In a study published in Nature Communications, Northwestern Medicine scientists detail the discovery of two types of cells in the retina that determine horizontal or vertical orientation, and demonstrated for the first time ...
Feb 26, 2018
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It's broadly assumed that cells degrade and recycle their own old or damaged organelles, but researchers at University of California, San Diego School of Medicine, The Johns Hopkins University School of Medicine and Kennedy ...
Jun 16, 2014
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