Researchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA sequencing to facilitate diagnoses of Mendelian disorders. The approach generated an overall diagnostic ...
Apr 9, 2024
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Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.
Jul 11, 2024
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Researchers at the University of California, San Diego School of Medicine have identified a new fusion protein found in approximately 15 percent of secondary glioblastomas or brain tumors. The finding offers new insights ...
Oct 14, 2014
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NRG Oncology GOG-0240 is the phase 3 randomized trial that demonstrated that the incorporation of bevacizumab with chemotherapy resulted in a statistically significant and clinically meaningful survival benefit for women ...
Mar 27, 2023
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Recent research has shown that tiny fragments of DNA circulating in a person's blood can allow scientists to monitor cancer growth and even get a sneak peek into a developing fetus' gene sequences. But isolating and sequencing ...
May 5, 2014
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On good days, the immune system can effectively handle pathogens that invade the body. However, when foreign matter takes the upper hand, the body builds a wall of immune cells called granuloma around the pathogens to isolate ...
Dec 7, 2023
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Comprehensive genetic testing of tumors and non-cancerous tissue from pediatric cancer patients is a feasible and clinically useful approach that can guide patient care, according to findings presented at the American Society ...
Oct 18, 2018
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Researchers from the Jan Dobeš laboratory at Charles University in Prague have made a significant discovery uncovering a novel immune response in the intestinal epithelium. Furthermore, their study delineates a mechanism ...
Oct 31, 2023
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Statistics is often thought of as an abstract branch of mathematics that relies on complex theoretical models and equations; for the layperson, the applications of such abstract modeling is not always immediately apparent.
May 11, 2020
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Researchers at Massachusetts General Hospital (MGH) have identified a potential mechanism by which tobacco smoking drives a type of white blood cell known as monocytes to the lung where they can increase the risk of active ...
Dec 13, 2023
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