Medical research

Regulating single protein prompts fibroblasts to become neurons

Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells – abundantly found in connective tissues – into functional neurons. The findings, which could have far-reaching implications ...

Medical research

Researchers explore origins of neuron diversity

SMU (Southern Methodist University) researchers have discovered another layer of complexity in gene expression, which could help explain how we're able to have so many billions of neurons in our brain.

Genetics

Understanding the effects of genes on human traits

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing ...

Oncology & Cancer

The factor that could influence future breast cancer treatment

Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...

Oncology & Cancer

RNA regulator of melanoma could be a new target for cancer therapy

Melanoma is the most deadly form of skin cancer, estimated by the National Cancer Institute to afflict more than 70,000 people in the United States annually and the incidence rate continues to rise. In a study published online ...

Alzheimer's disease & dementia

Researchers enter race for early Alzheimer's test

According to Paul Coleman, an Alzheimer's researcher at the ASU-Banner Neurodegenerative Disease Research Center (NDRC), one of the greatest difficulties plaguing efforts to find effective treatments for Alzheimer's is the ...

Diseases, Conditions, Syndromes

Study details microRNA's role as a double agent during Hep C infection

In the battle between a cell and a virus, either side may resort to subterfuge. Molecular messages, which control the cellular machinery both sides need, are vulnerable to interception or forgery. New research at Rockefeller ...

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