Diseases, Conditions, Syndromes

Researchers explore how Zika infection causes microcephaly

Infection with Zika virus disrupts fetal brain development by interfering with the proliferation of human neural progenitor cells (hNPCs), a type of cell that drives neurodevelopment and proliferates into brain and nervous ...

Diseases, Conditions, Syndromes

Zika virus: Optimized tests for reliable diagnosis

DZIF scientists from the University of Bonn have shown that not all conventional Zika virus molecular diagnostic tests for are sufficiently reliable. They developed optimised assays and a control for quantifying viruses in ...

Diseases, Conditions, Syndromes

A new paper-based test for the Zika virus

A new paper-based test developed at MIT and other institutions can diagnose Zika virus infection within a few hours. The test, which distinguishes Zika from the very similar dengue virus, can be stored at room temperature ...

Diseases, Conditions, Syndromes

New Zika mouse model accumulates virus in the brain and other tissues

The ongoing Zika virus (ZIKV) epidemic with its link to birth defects and serious immune disease has created an urgent need for a small animal model that can improve our understanding of how the virus causes disease symptoms ...

Diseases, Conditions, Syndromes

Hepatitis C virus uses Netrin-1 to hijack host cells

Hepatitis C virus (HCV) is a small, enveloped virus comprising an RNA genome encased in a protein capsid and surrounded by a lipid bilayer containing two glycoproteins. Acute infection can cause hepatitis but the virus usually ...

Diseases, Conditions, Syndromes

As Zika rages, scientists step up antiviral drug research

Samples of Zika virus from the outbreak raging across Brazil and Latin America arrived at the University of Washington last month, where they were quickly locked in a biosafety freezer, awaiting research aimed at stopping ...

Diseases, Conditions, Syndromes

Study shows high frequency of spontaneous mutation in Ebola virus

In late December, nearly two years after the epidemic began, the World Health Organization has declared the African country of Guinea to be free of Ebola virus infections. But, the race to find a cure and therapies to combat ...

Immunology

Compound found to trigger innate immunity against viruses

Research from UW Medicine and collaborators indicates that a drug-like molecule can activate innate immunity and induce genes to control infection in a range of RNA viruses, including West Nile, dengue, hepatitis C, influenza ...

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