Genetics

How genetic mutations promote Ewing's sarcoma

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have elucidated at the molecular level how an otherwise innocuous inherited mutation that is quite common in European populations interacts with a spontaneous ...

Oncology & Cancer

Researchers identify cell‑changing gene that can cause cancer

Researchers at Dalhousie Medical School have discovered that a gene found in a common herpes virus plays a key role in the development of several AIDS-related cancers – including a form of skin cancer known as Kaposi's ...

Oncology & Cancer

The key to stopping sarcomas' spread

When sarcomas become large enough and outgrow their blood supply, they become vulnerable to hypoxia—a lack of oxygen. That adaptation not only enables them to survive the stress of low oxygen—it also enables them to withstand ...

Oncology & Cancer

A noncoding RNA promotes pediatric bone cancer

Ewing sarcoma is a cancer of bone or its surrounding soft tissue that primarily affects children and young adults. A hallmark of Ewing sarcoma is a translocation event that results in the fusion of an RNA binding protein, ...

Oncology & Cancer

Possible new druggable target in Ewing's Sarcoma

Ewing's Sarcoma is an aggressive pediatric cancer, most commonly caused by the improper fusion of the gene EWS with the gene FLI1. Though the cause has long been known, therapeutic targeting of this fusion has to date proven ...

Oncology & Cancer

Viral microRNAs responsible for causing AIDS-related cancer

For the first time, scientists and engineers have identified a critical cancer-causing component in the virus that causes Kaposi's sarcoma, the most common cancer among HIV-infected people. The discovery lays the foundation ...

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