Oncology & Cancer

The key to stopping sarcomas' spread

When sarcomas become large enough and outgrow their blood supply, they become vulnerable to hypoxia—a lack of oxygen. That adaptation not only enables them to survive the stress of low oxygen—it also enables them to withstand ...

Oncology & Cancer

Possible new druggable target in Ewing's Sarcoma

Ewing's Sarcoma is an aggressive pediatric cancer, most commonly caused by the improper fusion of the gene EWS with the gene FLI1. Though the cause has long been known, therapeutic targeting of this fusion has to date proven ...

Oncology & Cancer

Viral microRNAs responsible for causing AIDS-related cancer

For the first time, scientists and engineers have identified a critical cancer-causing component in the virus that causes Kaposi's sarcoma, the most common cancer among HIV-infected people. The discovery lays the foundation ...

Oncology & Cancer

Two-drug combo more effective in treating sarcomas, study shows

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors. They report ...

Oncology & Cancer

Mouse model improves understanding of clear cell sarcoma

Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue ...

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