Oncology & Cancer

How tumors make immune cells 'go bad'

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting. The study, published today in ...

Oncology & Cancer

Researchers uncover crucial gene for growth of Ewing sarcoma

Researchers at the Institut de Recerca Sant Joan de Déu (IRSJD) in collaboration with those at Center for Genomic Regulation (CRG) have discovered that RING1B is a critical gene for the development of Ewing sarcoma, a rare ...

Medical research

New study advances understanding of rare sarcoma

Advancing the understanding of synovial sarcoma, a highly aggressive and rare cancer of young people, scientists at Dana-Farber Cancer Institute have discovered how an abnormal protein misdirects and disrupts the control ...

Oncology & Cancer

Immune cells hampered when fighting soft tissue and bone sarcomas

Aggregates of immune cells known as tertiary lymphoid structures (TLSs), seen here within a tumor of the soft tissues known as a rhabdomyosarcoma, are major players in the immune system's fight against cancer. Johns Hopkins ...

Oncology & Cancer

Cancer research: The genetic context is crucial

A team at Ludwig-Maximilians-Universitaet (LMU) in Munich has uncovered a mechanism behind the variability in the clinical course of Ewing sarcoma. The interaction between the acquired driver mutation and the germline genetic ...

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