Cardiology

A sobering conclusion: Adult hearts contain no stem cells

A detailed cell-by-cell map of all dividing cells in the adult murine heart before and after myocardial infarction was created using advanced molecular and genetic technologies in a combined research effort led by Hans Clevers ...

Medical research

Cells beneath the skin explain differences in healing

Differences in the cells that give skin its resilience and strength during wound repair may explain why individuals heal differently, according to a new Yale study published Nov. 23 in the journal Science.

Diseases, Conditions, Syndromes

Breakthrough for treatment of fibrotic diseases

Scientists have discovered a drug combination that could halt the progression of fibrosis—a condition believed to be responsible for almost half of all deaths—according to a study published in the journal European Urology.

Cardiology

A molecular atlas of postnatal mouse heart development

Myocardial infarction (MI) is one of the most common causes of death in the Western world. Typically, MI is caused by the blockage of a coronary artery by an atherosclerotic plaque: as the oxygen supply of the heart drops, ...

Medical research

Skin wounds in older mice are less likely to scar

Researchers have discovered a rare example in which the mammalian body functions better in old age. A team at the University of Pennsylvania found that, in skin wounds in mice, being older increased tissue regeneration and ...

Neuroscience

New sensors track dopamine in the brain for more than year

Dopamine, a signaling molecule used throughout the brain, plays a major role in regulating our mood, as well as controlling movement. Many disorders, including Parkinson's disease, depression, and schizophrenia, are linked ...

Medical research

Rogue molecules provoke out-of-control scar tissue, strangle organs

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases—kidney, liver and lung fibrosis—the scar tissue goes rogue and strangles vital organs. These diseases ...

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