Aging coincides with the accumulation of senescent cells within skeletal muscle that produce inflammatory products, known as the senescence-associated secretory phenotype, but the relationship of senescent cells to muscle ...
Apr 3, 2023
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Stress - defined broadly - can have a profoundly deleterious effect on the human body. Even individual cells have their own way of dealing with environmental strains such as ultraviolet radiation from the sun or germs. One ...
Oct 4, 2017
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Cells that have permanently stopped multiplying, so-called senescent cells, could play an important role in the fight against cancer, according to a new study in mice by researchers at Karolinska Institutet and IRB Barcelona. ...
Nov 3, 2022
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A new research paper was published on the cover of Aging entitled, "p21 facilitates chronic lung inflammation via epithelial and endothelial cells."
Apr 17, 2023
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Aging is a multifaceted process that affects our bodies in many ways. In a new study, researchers from Osaka University developed a novel vaccine that removes aged immune cells and then demonstrated an improvement of diabetes-associated ...
Jun 30, 2020
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An arrest in cell proliferation, also referred to as cellular senescence, occurs as a natural result of aging and in response to cellular stress. Senescent cells accumulate with age and are associated with many aging phenotypes, ...
Nov 15, 2013
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Mammals have a poor ability to recover after a spinal cord injury, which can result in paralysis. A main reason for this is the formation of a complex scar associated with chronic inflammation that produces a cellular microenvironment ...
Jul 6, 2021
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Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In a new paper, Ohanna et al. reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") ...
Jun 6, 2011
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Community-acquired pneumonia is the leading cause of infectious death among the elderly. Newly published research from The University of Texas Health Science Center San Antonio suggests why older people are vulnerable and ...
May 26, 2011
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Despite decades of research, Alzheimer's disease remains a debilitating and eventually fatal dementia with no effective treatment options. More than 95 percent of Alzheimer's disease cases have no known origin. Now, scientists ...
Dec 1, 2022
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