After decades of fundamental scientific and drug discovery research, Alzheimer's disease has remained inscrutable and incurable, with a bare minimum of therapeutic progress. But in a new review article in Nature Neuroscience, ...
Jan 3, 2023
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Changes to the structure of the protein histone H3.3 may play a key role in silencing genes that regulate cancer cell growth, according to a study led by researchers from the Icahn School of Medicine at Mount Sinai and published ...
Nov 21, 2014
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Liver cancer's rapid growth leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at ...
Aug 2, 2022
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Senescent cells—those that have lost the ability to divide—accumulate with age and are key drivers of age-related diseases, such as cancer, dementia and cardiovascular disease. In a new study, a team led by University ...
Jun 30, 2022
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Older adults with depression are actually aging faster than their peers, UConn Center on Aging researchers report.
Mar 22, 2023
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Permanently arrested cell growth is known as "cellular senescence", and the accumulation of senescent cells may be one cause of aging in our bodies. Japanese researchers have discovered that a certain enzyme in our bodies ...
Jan 24, 2019
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A recent study, led by an international team of researchers confirms that targeted removal of senescent cells (SnCs), accumulated in many vertebrate tissues as we age, contribute significantly in delaying the onset of age-related ...
Jun 9, 2017
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Atherosclerosis is a disease in which arteries narrow due to plaques. That narrowing can lead to heart attacks and strokes—both of which are leading causes of death in the U.S. Now, in a paper published in Science, Mayo ...
Oct 27, 2016
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Senescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has revealed that senescent cells play important roles in a growing list of diseases from cancer, ...
Oct 21, 2019
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You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis—which can help the elderly bounce back faster ...
Jul 25, 2023
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