Medications
Drug that kills off sleeping bone cells could treat lower back pain
An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study.
Nov 14, 2023
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Page 18 - News tagged with senescent cells
Medical research
Cellular senescence prevented by the SETD8 enzyme
An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates cell proliferation and ...
Mar 8, 2017
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Diseases, Conditions, Syndromes
Taking on harmful cells that contribute to age-related diseases
It's not the fountain of youth, but a fast-emerging class of drugs could bring us closer to achieving the age-old quest for longer life, better health, and greater vitality.
Jun 23, 2021
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Health
Why do older people heal more slowly?
I recently visited an 83-year-old patient in the hospital after EMTs rushed her to the ER with an infected leg wound. Her ordeal started inconspicuously when she bumped into the sharp edge of a table and developed a small ...
Nov 24, 2020
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Oncology & Cancer
Senescence promotes chemotherapy side effects and cancer relapse
Standard chemotherapy is a blunt force instrument against cancer – and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, ...
Jan 17, 2017
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Medical research
Long-term benefits of 'senolytic' drugs on vascular health in mice
Building on previous studies, Mayo Clinic researchers have demonstrated significant health improvements in the vascular system of mice following repeated treatments to remove senescent cells. They say this is the first study ...
Feb 11, 2016
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Diseases, Conditions, Syndromes
Research reveals how aging cells can be an underlying cause of kidney damage
A study in mice by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that stress and tissue damage initiated by angiotensin II, a molecule that is known to increase blood pressure and stiffening in ...
Dec 8, 2021
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Medical research
Effects of zoledronic acid on senescence and SASP markers
A new research paper, titled "In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers," was published on the cover of Aging
May 15, 2023
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Oncology & Cancer
Study finds senescent immune cells promote lung tumor growth
Macrophages are a type of white blood cell that are among the body's first line of defense against infection. In addition to killing harmful microorganisms, macrophages typically can initiate a response against tumors. However, ...
Sep 26, 2023
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Gerontology & Geriatrics
DNA damage-induced senescence model in osteoarthritic chondrocytes
A new research paper titled "Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes" has been published in Aging.
Sep 20, 2023
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