Medical research

Researchers discover new cause of cell aging

New research from the USC Viterbi School of Engineering could be key to our understanding of how the aging process works. The findings potentially pave the way for better cancer treatments and revolutionary new drugs that ...

Medical research

The immune system's fountain of youth

If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly obtainable in the future. ...

Immunology

Obesity: What has immunity got to do with it?

As organisms grow, older cells can undergo a phenomenon called senescence. This process defines a cell state where cells permanently stop dividing but do not die. Senescent cells secrete toxic pro-inflammatory factors contributing ...

Neuroscience

The pathway to Parkinson's takes a surprising twist

In neurodegenerative conditions like Parkinson's disease, a specific group of neurons start to die one by one, causing movement problems and other symptoms. Scientists have long focused on finding out why these neurons die. ...

Medical research

Scientists find mechanism that eliminates senescent cells

Scientists at UC San Francisco are learning how immune cells naturally clear the body of defunct—or senescent—cells that contribute to aging and many chronic diseases. Understanding this process may open new ways of treating ...

Medical research

Senolytic drugs reverse damage caused by senescent cells in mice

Injecting senescent cells into young mice results in a loss of health and function but treating the mice with a combination of two existing drugs cleared the senescent cells from tissues and restored physical function. The ...

Medical research

Medical researchers decoding the aging process

Scientists are beginning to decode the complex biology of aging and are optimistic that recent advances in research may lead to treatments that can slow or even reverse degeneration and disease.

Medical research

Obese mice lose anxiety when 'zombie cells' exit their brain

Mayo Clinic researchers and collaborators have shown in mice that obesity increases the level of "zombie" or senescent cells in the brain, and that those cells, in turn, are linked to anxiety. When senolytic drugs are used ...

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